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8-Nitroguanosine formation in viral pneumonia and its implication for pathogenesis

For many diseases, mediation of pathogenesis by nitric oxide (NO) has been suggested. In this study, we explored NO-induced viral pathogenesis with a focus on nucleic acid damage as evidenced by 8-nitroguanosine formation in vivo. Wild-type mice and littermate mice deficient in inducible NO synthase...

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Bibliografische Detailangaben
Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Akaike, Takaaki, Okamoto, Shinichiro, Sawa, Tomohiro, Yoshitake, Jun, Tamura, Fumio, Ichimori, Koji, Miyazaki, Kiminori, Sasamoto, Kazumi, Maeda, Hiroshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2003
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC141057/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12522148/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0235623100
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