8-Nitroguanosine formation in viral pneumonia and its implication for pathogenesis

For many diseases, mediation of pathogenesis by nitric oxide (NO) has been suggested. In this study, we explored NO-induced viral pathogenesis with a focus on nucleic acid damage as evidenced by 8-nitroguanosine formation in vivo. Wild-type mice and littermate mice deficient in inducible NO synthase...

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Autores principales: Akaike, Takaaki, Okamoto, Shinichiro, Sawa, Tomohiro, Yoshitake, Jun, Tamura, Fumio, Ichimori, Koji, Miyazaki, Kiminori, Sasamoto, Kazumi, Maeda, Hiroshi
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences 2003
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC141057/
https://ncbi.nlm.nih.gov/pubmed/12522148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0235623100
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