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Assembly of single chromatin fibers depends on the tension in the DNA molecule: Magnetic tweezers study

We have used magnetic tweezers to study in real time chaperone-mediated chromatin assembly/disassembly at the level of single chromatin fibers. We find a strong dependence of the rate of assembly on the exerted force, with strong inhibition of assembly at forces exceeding 10 pN. During assembly, and...

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書誌詳細
主要な著者: Leuba, Sanford H., Karymov, Mikhail A., Tomschik, Miroslav, Ramjit, Ravi, Smith, Paul, Zlatanova, Jordanka
フォーマット: Artigo
言語:Inglês
出版事項: The National Academy of Sciences 2003
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC141023/
https://ncbi.nlm.nih.gov/pubmed/12522259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0136890100
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