The Natural Host Range Shift and Subsequent Evolution of Canine Parvovirus Resulted from Virus-Specific Binding to the Canine Transferrin Receptor

Canine parvovirus (CPV) is a host range variant of a feline virus that acquired the ability to infect dogs through changes in its capsid protein. Canine and feline viruses both use the feline transferrin receptor (TfR) to infect feline cells, and here we show that CPV infects canine cells through it...

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Main Authors: Hueffer, Karsten, Parker, John S. L., Weichert, Wendy S., Geisel, Rachel E., Sgro, Jean-Yves, Parrish, Colin R.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2003
Assuntos:
Virus-Cell Interactions
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC140992/
https://ncbi.nlm.nih.gov/pubmed/12525605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.3.1718-1726.2003
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