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Divergent Effects of BMP-2 on Gene Expression in Pulmonary Artery Smooth Muscle Cells from Normal Subjects and Patients with Idiopathic Pulmonary Arterial Hypertension

Bone morphogenetic proteins (BMP) inhibit proliferation and induce apoptosis in pulmonary artery smooth muscle cells (PASMC) from normal subjects. Dysfunction of BMP signaling due to mutations in and/or downregulation of BMP receptors has been implicated in idiopathic pulmonary arterial hypertension...

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Bibliografski detalji
Glavni autori: Fantozzi, Ivana, Huang, Wei, Zhang, Jifeng, Zhang, Shen, Platoshyn, Oleksandr, Remillard, Carmelle V., Thistlethwaite, Patricia A., Yuan, Jason X.-J.
Format: Artigo
Jezik:Inglês
Izdano: 2005
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1409757/
https://ncbi.nlm.nih.gov/pubmed/16368652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/01902140500461026
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