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Divergent Effects of BMP-2 on Gene Expression in Pulmonary Artery Smooth Muscle Cells from Normal Subjects and Patients with Idiopathic Pulmonary Arterial Hypertension

Bone morphogenetic proteins (BMP) inhibit proliferation and induce apoptosis in pulmonary artery smooth muscle cells (PASMC) from normal subjects. Dysfunction of BMP signaling due to mutations in and/or downregulation of BMP receptors has been implicated in idiopathic pulmonary arterial hypertension...

詳細記述

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書誌詳細
主要な著者: Fantozzi, Ivana, Huang, Wei, Zhang, Jifeng, Zhang, Shen, Platoshyn, Oleksandr, Remillard, Carmelle V., Thistlethwaite, Patricia A., Yuan, Jason X.-J.
フォーマット: Artigo
言語:Inglês
出版事項: 2005
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1409757/
https://ncbi.nlm.nih.gov/pubmed/16368652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/01902140500461026
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