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Divergent Effects of BMP-2 on Gene Expression in Pulmonary Artery Smooth Muscle Cells from Normal Subjects and Patients with Idiopathic Pulmonary Arterial Hypertension

Bone morphogenetic proteins (BMP) inhibit proliferation and induce apoptosis in pulmonary artery smooth muscle cells (PASMC) from normal subjects. Dysfunction of BMP signaling due to mutations in and/or downregulation of BMP receptors has been implicated in idiopathic pulmonary arterial hypertension...

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Bibliografische gegevens
Hoofdauteurs: Fantozzi, Ivana, Huang, Wei, Zhang, Jifeng, Zhang, Shen, Platoshyn, Oleksandr, Remillard, Carmelle V., Thistlethwaite, Patricia A., Yuan, Jason X.-J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2005
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1409757/
https://ncbi.nlm.nih.gov/pubmed/16368652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/01902140500461026
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