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Amplification and disruption of the phenylacetyl-CoA ligase gene of Penicillium chrysogenum encoding an aryl-capping enzyme that supplies phenylacetic acid to the isopenicillin N-acyltransferase

A gene, phl, encoding a phenylacetyl-CoA ligase was cloned from a phage library of Penicillium chrysogenum AS-P-78. The presence of five introns in the phl gene was confirmed by reverse transcriptase-PCR. The phl gene encoded an aryl-CoA ligase closely related to Arabidopsis thaliana 4-coumaroyl-CoA...

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Main Authors: Lamas-Maceiras, Mónica, Vaca, Inmaculada, Rodríguez, Esther, Casqueiro, Javier, Martín, Juan F.
Formato: Artigo
Idioma:Inglês
Publicado: Portland Press Ltd. 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1409706/
https://ncbi.nlm.nih.gov/pubmed/16321143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20051599
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