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Epidermal growth factor-regulated activation of Rac GTPase enhances CD44 cleavage by metalloproteinase disintegrin ADAM10

Invasive tumour cells, such as gliomas, frequently express EGF (epidermal growth factor) receptor at a high level and they exhibit enhanced cell migration in response to EGF. We reported previously that tumour cell migration is associated with ectodomain cleavage of CD44, the major adhesion molecule...

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Bibliografische gegevens
Hoofdauteurs: Murai, Toshiyuki, Miyauchi, Takayuki, Yanagida, Toshio, Sako, Yasushi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Portland Press Ltd. 2006
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1409701/
https://ncbi.nlm.nih.gov/pubmed/16390331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20050582
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