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Epidermal growth factor-regulated activation of Rac GTPase enhances CD44 cleavage by metalloproteinase disintegrin ADAM10

Invasive tumour cells, such as gliomas, frequently express EGF (epidermal growth factor) receptor at a high level and they exhibit enhanced cell migration in response to EGF. We reported previously that tumour cell migration is associated with ectodomain cleavage of CD44, the major adhesion molecule...

詳細記述

保存先:
書誌詳細
主要な著者: Murai, Toshiyuki, Miyauchi, Takayuki, Yanagida, Toshio, Sako, Yasushi
フォーマット: Artigo
言語:Inglês
出版事項: Portland Press Ltd. 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1409701/
https://ncbi.nlm.nih.gov/pubmed/16390331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20050582
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