Peroxisome-proliferator-activated receptor α agonists inhibit cyclo-oxygenase 2 and vascular endothelial growth factor transcriptional activation in human colorectal carcinoma cells via inhibition of activator protein-1

Recent evidence indicates that PPAR (peroxisome-proliferator-activated receptor) α ligands possess anti-inflammatory and antitumoural properties owing to their inhibitory effects on the expression of genes that are involved in the inflammatory response. However, the precise molecular mechanisms unde...

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Hlavní autoři: Grau, Raquel, Punzón, Carmen, Fresno, Manuel, Iñiguez, Miguel A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Portland Press Ltd. 2006
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1409694/
https://ncbi.nlm.nih.gov/pubmed/16343055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20050964
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