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Overlapping Motifs (PTAP and PPEY) within the Ebola Virus VP40 Protein Function Independently as Late Budding Domains: Involvement of Host Proteins TSG101 and VPS-4

The VP40 protein of Ebola virus can bud from mammalian cells in the form of lipid-bound, virus-like particles (VLPs), and late budding domains (L-domains) are conserved motifs (PTAP, PPxY, or YxxL; where “x” is any amino acid) that facilitate the budding of VP40-containing VLPs. VP40 is unique in th...

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Detalhes bibliográficos
Main Authors: Licata, Jillian M., Simpson-Holley, Martha, Wright, Nathan T., Han, Ziying, Paragas, Jason, Harty, Ronald N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC140960/
https://ncbi.nlm.nih.gov/pubmed/12525615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.3.1812-1819.2003
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