Disrupted-in-Schizophrenia-1 (DISC-1): Mutant truncation prevents binding to NudE-like (NUDEL) and inhibits neurite outgrowth

Disrupted-in-Schizophrenia-1 (DISC-1) is a gene whose mutant truncation is associated with major psychiatric illness with a predominance of schizophrenic symptomatology. We have cloned and characterized rodent DISC-1. DISC-1 expression displays pronounced developmental regulation with the highest le...

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Detalles Bibliográficos
Main Authors: Ozeki, Yuji, Tomoda, Toshifumi, Kleiderlein, John, Kamiya, Atsushi, Bord, Lyuda, Fujii, Kumiko, Okawa, Masako, Yamada, Naoto, Hatten, Mary E., Snyder, Solomon H., Ross, Christopher A., Sawa, Akira
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 2003
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC140954/
https://ncbi.nlm.nih.gov/pubmed/12506198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0136913100
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