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A Structurally Disordered Region at the C Terminus of Capsid Plays Essential Roles in Multimerization and Membrane Binding of the Gag Protein of Human Immunodeficiency Virus Type 1

Crystal structures of human immunodeficiency virus type 1 (HIV-1) capsid protein (CA) reveal that the last 11 C-terminal amino acids are disordered. This disordered region contains a glycine-rich sequence 353-GVGGP-357 (numbering refers to the initiation methionine of Gag) that is highly conserved w...

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Hlavní autoři: Liang, Chen, Hu, Jing, Whitney, James B., Kleiman, Lawrence, Wainberg, Mark A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC140948/
https://ncbi.nlm.nih.gov/pubmed/12525611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.3.1772-1783.2003
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