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Expression of Th1-mediated immunity in mouse lungs induces a Mycobacterium tuberculosis transcription pattern characteristic of nonreplicating persistence

The lung is the primary target of infection with Mycobacterium tuberculosis. It is well established that, in mouse lung, expression of adaptive, Th1-mediated host immunity inhibits further multiplication of M. tuberculosis. Here, real-time RT-PCR was used to define the pattern of expression against...

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Bibliographische Detailangaben
Hauptverfasser: Shi, Lanbo, Jung, Yu-Jin, Tyagi, Sanjay, Gennaro, Maria Laura, North, Robert J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC140939/
https://ncbi.nlm.nih.gov/pubmed/12506197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0136863100
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