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Expression of Th1-mediated immunity in mouse lungs induces a Mycobacterium tuberculosis transcription pattern characteristic of nonreplicating persistence

The lung is the primary target of infection with Mycobacterium tuberculosis. It is well established that, in mouse lung, expression of adaptive, Th1-mediated host immunity inhibits further multiplication of M. tuberculosis. Here, real-time RT-PCR was used to define the pattern of expression against...

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Detalhes bibliográficos
Main Authors: Shi, Lanbo, Jung, Yu-Jin, Tyagi, Sanjay, Gennaro, Maria Laura, North, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC140939/
https://ncbi.nlm.nih.gov/pubmed/12506197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0136863100
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