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Evidence for the widespread coupling of alternative splicing and nonsense-mediated mRNA decay in humans

To better understand the role of alternative splicing, we conducted a large-scale analysis of reliable alternative isoforms of known human genes. Each isoform was classified according to its splice pattern and supporting evidence. We found that one-third of the alternative transcripts examined conta...

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Détails bibliographiques
Auteurs principaux: Lewis, Benjamin P., Green, Richard E., Brenner, Steven E.
Format: Artigo
Langue:Inglês
Publié: The National Academy of Sciences 2003
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC140922/
https://ncbi.nlm.nih.gov/pubmed/12502788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0136770100
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