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The Foot-and-Mouth Disease Virus cis-Acting Replication Element (cre) Can Be Complemented in trans within Infected Cells

A temperature-sensitive (ts) mutation was identified within the 5′-untranslated region of foot-and-mouth disease virus (FMDV) RNA. The mutation destabilizes a stem-loop structure recently identified as a cis-acting replication element (cre). Genetic analyses indicated that the ts defect in virus rep...

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Detalhes bibliográficos
Main Authors: Tiley, Laurence, King, Andrew M. Q., Belsham, Graham J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC140903/
https://ncbi.nlm.nih.gov/pubmed/12525659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.3.2243-2246.2003
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