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The Foot-and-Mouth Disease Virus cis-Acting Replication Element (cre) Can Be Complemented in trans within Infected Cells

A temperature-sensitive (ts) mutation was identified within the 5′-untranslated region of foot-and-mouth disease virus (FMDV) RNA. The mutation destabilizes a stem-loop structure recently identified as a cis-acting replication element (cre). Genetic analyses indicated that the ts defect in virus rep...

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Udgivet i:J Virol
Principais autores: Tiley, Laurence, King, Andrew M. Q., Belsham, Graham J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2003
Fag:
Replication
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140903/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12525659/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.3.2243-2246.2003
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