Binding of the Hepatitis C Virus E2 Glycoprotein to CD81 Is Strain Specific and Is Modulated by a Complex Interplay between Hypervariable Regions 1 and 2

The envelope glycoprotein E2 of hepatitis C virus (HCV) is the target of neutralizing antibodies and is presently being evaluated as an HCV vaccine candidate. HCV binds to human cells through the interaction of E2 with the tetraspanin CD81, a putative viral receptor component. We have analyzed four...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Roccasecca, RosaMaria, Ansuini, Helenia, Vitelli, Alessandra, Meola, Annalisa, Scarselli, Elisa, Acali, Stefano, Pezzanera, Monica, Ercole, Bruno Bruni, McKeating, Jane, Yagnik, Asutosh, Lahm, Armin, Tramontano, Anna, Cortese, Riccardo, Nicosia, Alfredo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2003
Pynciau:
Virus-Cell Interactions
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC140892/
https://ncbi.nlm.nih.gov/pubmed/12525620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.3.1856-1867.2003
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