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Reconstruction of human hepatocyte glyoxylate metabolic pathways in stably transformed Chinese-hamster ovary cells

Failure to detoxify the intermediary metabolite glyoxylate in human hepatocytes underlies the metabolic pathology of two potentially lethal hereditary calcium oxalate kidney stone diseases, PH (primary hyperoxaluria) types 1 and 2. In order to define more clearly the roles of enzymes involved in the...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Behnam, Joseph T., Williams, Emma L., Brink, Susanne, Rumsby, Gill, Danpure, Christopher J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Portland Press Ltd. 2006
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1408671/
https://ncbi.nlm.nih.gov/pubmed/16309382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20051397
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