The Clearance of Hepatitis C Virus Infection in Chimpanzees May Not Necessarily Correlate with the Appearance of Acquired Immunity

Clearance of hepatitis C virus (HCV) infection in humans and chimpanzees is thought to be associated with the induction of strong T-cell responses. We studied four chimpanzees infected with HCV derived from an infectious full-length HCV genotype 1b cDNA. Two of the chimpanzees cleared the infection...

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Bibliographic Details
Main Authors: Thomson, Michael, Nascimbeni, Michelina, Havert, Michael B., Major, Marian, Gonzales, Sophia, Alter, Harvey, Feinstone, Stephen M., Murthy, Krishna K., Rehermann, Barbara, Liang, T. Jake
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC140840/
https://ncbi.nlm.nih.gov/pubmed/12502802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.2.862-870.2003
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