Amino Acid Residues 88 and 89 in the Central Hydrophilic Region of Human Immunodeficiency Virus Type 1 Vif Are Critical for Viral Infectivity by Enhancing the Steady-State Expression of Vif

A hydrophilic region consisting of strikingly clustered charged amino acids is present at the center of human immunodeficiency virus type 1 (HIV-1) Vif. In this study, the role for this central hydrophilic region (E(88)WRKKR(93)) in the virus replication in nonpermissive H9 cells was investigated by...

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Detalhes bibliográficos
Main Authors: Fujita, Mikako, Sakurai, Akiko, Yoshida, Akiko, Miyaura, Maki, Koyama, A. Hajime, Sakai, Koji, Adachi, Akio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC140823/
https://ncbi.nlm.nih.gov/pubmed/12502880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.2.1626-1632.2003
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