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Expression Level of HIV-1 Vif Can Be Fluctuated by Natural Nucleotide Variations in the vif-Coding and Regulatory SA1D2prox Sequences of the Proviral Genome

Vif is required for HIV-1 replication in natural target cells by counteracting host restriction factors, APOBEC3 (A3) proteins. We recently demonstrated that Vif expression level can be changed by naturally occurring single-nucleotide variations within SA1D2prox of the HIV-1 genome. We also found th...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Doi, Naoya, Koma, Takaaki, Adachi, Akio, Nomaguchi, Masako
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6893887/
https://ncbi.nlm.nih.gov/pubmed/31849897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2019.02758
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