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The Dihydrofolate Reductase Origin of Replication Does Not Contain Any Nonredundant Genetic Elements Required for Origin Activity
The Chinese hamster dihydrofolate reductase (DHFR) origin of replication consists of a broad zone of potential initiation sites scattered throughout a 55-kb intergenic spacer, with at least three sites being preferred (ori-β, ori-β′, and ori-γ). We previously showed that deletion of the most active...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology
2003
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC140713/ https://ncbi.nlm.nih.gov/pubmed/12529386 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.3.804-814.2003 |
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