Loss of S100A9 (MRP14) Results in Reduced Interleukin-8-Induced CD11b Surface Expression, a Polarized Microfilament System, and Diminished Responsiveness to Chemoattractants In Vitro

The S100A9 (MRP14) protein is abundantly expressed in myeloid cells and has been associated with various inflammatory diseases. The S100A9-deficient mice described here were viable, fertile, and generally of healthy appearance. The myelopoietic potential of the S100A9-null bone marrow was normal. S1...

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Autores principales: Manitz, Marie-Pierre, Horst, Basil, Seeliger, Stephan, Strey, Anke, Skryabin, Boris V., Gunzer, Matthias, Frings, Werner, Schönlau, Frank, Roth, Johannes, Sorg, Clemens, Nacken, Wolfgang
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2003
Materias:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC140712/
https://ncbi.nlm.nih.gov/pubmed/12529407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.3.1034-1043.2003
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