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R-Ras Promotes Focal Adhesion Formation through Focal Adhesion Kinase and p130(Cas) by a Novel Mechanism That Differs from Integrins

R-Ras regulates integrin function, but its effects on integrin signaling pathways have not been well described. We demonstrate that activation of R-Ras promoted focal adhesion formation and altered localization of the α2β1 integrin from cell-cell to cell-matrix adhesions in breast epithelial cells....

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Библиографические подробности
Главные авторы: Kwong, Lina, Wozniak, Michele A., Collins, Asha S., Wilson, Siobhan D., Keely, Patricia J.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2003
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC140691/
https://ncbi.nlm.nih.gov/pubmed/12529399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.3.933-949.2003
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