Induction of Apoptosis by Sphingoid Long-Chain Bases in Aspergillus nidulans

Sphingolipid metabolism is implicated to play an important role in apoptosis. Here we show that dihydrosphingosine (DHS) and phytosphingosine (PHS), two major sphingoid bases of fungi, have potent fungicidal activity with remarkably high structural and stereochemical specificity against Aspergillus...

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Bibliografiske detaljer
Main Authors: Cheng, Jijun, Park, Tae-Sik, Chio, Li-Chun, Fischl, Anthony S., Ye, Xiang S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2003
Fag:
Cell Growth and Development
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC140675/
https://ncbi.nlm.nih.gov/pubmed/12482970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.1.163-177.2003
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