Induction of Apoptosis by Sphingoid Long-Chain Bases in Aspergillus nidulans

Sphingolipid metabolism is implicated to play an important role in apoptosis. Here we show that dihydrosphingosine (DHS) and phytosphingosine (PHS), two major sphingoid bases of fungi, have potent fungicidal activity with remarkably high structural and stereochemical specificity against Aspergillus...

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Detalhes bibliográficos
Main Authors: Cheng, Jijun, Park, Tae-Sik, Chio, Li-Chun, Fischl, Anthony S., Ye, Xiang S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC140675/
https://ncbi.nlm.nih.gov/pubmed/12482970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.1.163-177.2003
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