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Marker Rescue of Adeno-Associated Virus (AAV) Capsid Mutants: a Novel Approach for Chimeric AAV Production

Marker rescue, the restoration of gene function by replacement of a defective gene with a normal one by recombination, has been utilized to produce novel adeno-associated virus (AAV) vectors. AAV serotype 2 (AAV2) clones containing wild-type terminal repeats, an intact rep gene, and a mutated cap ge...

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Foilsithe in:J Virol
Príomhchruthaitheoirí: Bowles, Dawn E., Rabinowitz, Joseph E., Samulski, R. Jude
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: American Society for Microbiology (ASM) 2003
Ábhair:
Rochtain ar líne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140636/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12477847/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.1.423-432.2003
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