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Marker Rescue of Adeno-Associated Virus (AAV) Capsid Mutants: a Novel Approach for Chimeric AAV Production

Marker rescue, the restoration of gene function by replacement of a defective gene with a normal one by recombination, has been utilized to produce novel adeno-associated virus (AAV) vectors. AAV serotype 2 (AAV2) clones containing wild-type terminal repeats, an intact rep gene, and a mutated cap ge...

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Hlavní autoři: Bowles, Dawn E., Rabinowitz, Joseph E., Samulski, R. Jude
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC140636/
https://ncbi.nlm.nih.gov/pubmed/12477847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.1.423-432.2003
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