Fine Mapping of the Interaction of Neutralizing and Nonneutralizing Monoclonal Antibodies with the CD4 Binding Site of Human Immunodeficiency Virus Type 1 gp120

Alanine scanning mutagenesis was performed on monomeric gp120 of human immunodeficiency virus type 1 to systematically identify residues important for gp120 recognition by neutralizing and nonneutralizing monoclonal antibodies (MAbs) to the CD4 binding site (CD4bs). Substitutions that affected the b...

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Publicado en:	J Virol
Autores principales:	Pantophlet, Ralph, Ollmann Saphire, Erica, Poignard, Pascal, Parren, Paul W. H. I., Wilson, Ian A., Burton, Dennis R.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 2003
Materias:	Structure and Assembly
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140633/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12477867/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.1.642-658.2003
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