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Functional Replacement of Nucleocapsid Flanking Regions by Heterologous Counterparts with Divergent Primary Sequences: Effects of Chimeric Nucleocapsid on the Retroviral Replication Cycle
Nucleocapsid (NC) proteins in most retroviruses have a well-conserved Cys-His box(es) as well as more divergent flanking regions that are rich in basic residues. Mutations in the flanking regions can affect RNA packaging, virus assembly, and reverse transcription of the viral RNA. To gain a further...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2003
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| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC140598/ https://ncbi.nlm.nih.gov/pubmed/12477882 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.1.754-761.2003 |
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