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Functional Replacement of Nucleocapsid Flanking Regions by Heterologous Counterparts with Divergent Primary Sequences: Effects of Chimeric Nucleocapsid on the Retroviral Replication Cycle

Nucleocapsid (NC) proteins in most retroviruses have a well-conserved Cys-His box(es) as well as more divergent flanking regions that are rich in basic residues. Mutations in the flanking regions can affect RNA packaging, virus assembly, and reverse transcription of the viral RNA. To gain a further...

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Detalhes bibliográficos
Principais autores: Fu, William, Hu, Wei-Shau
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC140598/
https://ncbi.nlm.nih.gov/pubmed/12477882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.1.754-761.2003
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