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Delineation of the high-affinity single-stranded telomeric DNA-binding domain of Saccharomyces cerevisiae Cdc13

Cdc13 is an essential protein from Saccharomyces cerevisiae that caps telomeres by protecting the C-rich telomeric DNA strand from degradation and facilitates telomeric DNA replication by telomerase. In vitro, Cdc13 binds TG-rich single-stranded telomeric DNA with high affinity and specificity. A pr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Anderson, Emily M., Halsey, Wayne A., Wuttke, Deborah S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC140553/
https://ncbi.nlm.nih.gov/pubmed/12364610
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