Reversible inhibition of the second step of splicing suggests a possible role of zinc in the second step of splicing

A multicomponent complex of proteins and RNA is assembled on the newly synthesized pre-mRNA to form the spliceosome. This complex catalyzes a two-step transesterification reaction required to remove the introns and ligate the exons. To date, only six proteins have been found necessary for the second...

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Pubblicato in:	Nucleic Acids Res
Autori principali:	Shomron, Noam, Malca, Hadar, Vig, Ida, Ast, Gil
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Oxford University Press 2002
Soggetti:	Articles
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140552/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12364591/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkf553
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