Reversible inhibition of the second step of splicing suggests a possible role of zinc in the second step of splicing
A multicomponent complex of proteins and RNA is assembled on the newly synthesized pre-mRNA to form the spliceosome. This complex catalyzes a two-step transesterification reaction required to remove the introns and ligate the exons. To date, only six proteins have been found necessary for the second...
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| Publicado no: | Nucleic Acids Res |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140552/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12364591/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkf553 |
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