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HIV Protease Inhibitors Acutely Impair Glucose-Stimulated Insulin Release

HIV protease inhibitors (PIs) acutely and reversibly inhibit the insulin-responsive glucose transporter Glut 4, leading to peripheral insulin resistance and impaired glucose tolerance. Minimal modeling analysis of glucose tolerance tests on PI-treated patients has revealed an impaired insulin secret...

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Detalhes bibliográficos
Main Authors: Koster, Joseph C., Remedi, Maria S., Qiu, Haijun, Nichols, Colin G., Hruz, Paul W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1403824/
https://ncbi.nlm.nih.gov/pubmed/12829635
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