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Long-term starvation and ageing induce AGE-1/PI 3-kinase-dependent translocation of DAF-16/FOXO to the cytoplasm

BACKGROUND: The provision of stress resistance diverts resources from development and reproduction and must therefore be tightly regulated. In Caenorhabditis elegans, the switch to increased stress resistance to promote survival through periods of starvation is regulated by the DAF-16/FOXO transcrip...

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Detalhes bibliográficos
Main Authors: Weinkove, David, Halstead, Jonathan R, Gems, David, Divecha, Nullin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1403811/
https://ncbi.nlm.nih.gov/pubmed/16457721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7007-4-1
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