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Cellular Notch responsiveness is defined by phosphoinositide 3-kinase-dependent signals

BACKGROUND: Notch plays a wide-ranging role in controlling cell fate, differentiation and development. The PI3K-Akt pathway is a similarly conserved signalling pathway which regulates processes such as differentiation, proliferation and survival. Mice with disrupted Notch and PI3K signalling show ph...

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Detalhes bibliográficos
Main Authors: Mckenzie, Grahame, Ward, George, Stallwood, Yvette, Briend, Emmanuel, Papadia, Sofia, Lennard, Andrew, Turner, Martin, Champion, Brian, Hardingham, Giles E
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1403772/
https://ncbi.nlm.nih.gov/pubmed/16507111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-7-10
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