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Thiopurinol: Comparative enzyme inhibition and protein binding studies with allopurinol, oxipurinol and 6-mercaptopurine

1 The metabolites of thiopurinol have been investigated in intact human and pig erythrocytes using [6-(14)C]-thiopurinol, high voltage electrophoresis and automated cation exchange chromatography. 2 Pre-incubation of human erythrocytes in vitro with thiopurinol increased the formation of hypoxanthin...

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Autores principales: Dean, B. M., Perrett, D., Simmonds, H. A., Grahame, R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 1974
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1402452/
https://ncbi.nlm.nih.gov/pubmed/22454898
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