Comparison of the pharmacodynamic and pharmacokinetic profiles of single and multiple doses of a commercial slow-release metoprolol formulation with a new Oros delivery system.

1 A new osmotic pressure mediated delivery system for metoprolol (Lopresor Oros) has been evaluated by measuring the haemodynamic effects and pharmacokinetics after single and multiple oral dosing in young healthy volunteers. 2 Similar studies have been carried out in the same group using equivalent...

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Autores principales: Kendall, M J, Jack, D B, Woods, K L, Laugher, S J, Quarterman, C P, John, V A
Formato: Artigo
Lenguaje:Inglês
Publicado: 1982
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1402116/
https://ncbi.nlm.nih.gov/pubmed/7059440
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