Novel functional requirements for non-homologous DNA end joining in Schizosaccharomyces pombe

DNA double strand break (DSB) repair by non-homologous end joining (NHEJ) in mammalian cells requires the Ku70–Ku80 heterodimer, the DNA-PK catalytic subunit DNA-PKcs, as well as DNA ligase IV and Xrcc4. NHEJ of plasmid DSBs in Saccharomyces cerevisiae requires Ku, Xrcc4 and DNA ligase IV, as well a...

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Publié dans:	EMBO J
Auteurs principaux:	Manolis, Kostas G., Nimmo, Elaine R., Hartsuiker, Edgar, Carr, Antony M., Jeggo, Penny A., Allshire, Robin C.
Format:	Artigo
Langue:	Inglês
Publié:	Nature Publishing Group 2001
Sujets:	Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140209/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11226171/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.1.210
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