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Serum protein binding and free concentration of phenytoin and phenobarbitone in pregnancy.

1 The effect of pregnancy on the binding of phenytoin and phenobarbitone to serum proteins was studied in normal women and in drug treated epileptic women. 2 The binding of both drugs was reduced during pregnancy. The reduction correlated positively with the gestational age and negatively with the s...

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Detalhes bibliográficos
Main Authors: Chen, S S, Perucca, E, Lee, J N, Richens, A
Formato: Artigo
Idioma:Inglês
Publicado em: 1982
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1402062/
https://ncbi.nlm.nih.gov/pubmed/7066170
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