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Advanced Glycation End Products Activate a Chymase-Dependent Angiotensin II Generating Pathway in Diabetic Complications

Background: Angiotensin II is a key mediator of diabetes-related vascular disease. It is now recognized that in addition to angiotensin converting enzyme (ACE), chymase is an important alternative angiotensin II generating enzyme in hypertension and diabetes. However, the mechanism of induction of c...

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Detalhes bibliográficos
Main Authors: Koka, Vijay, Wang, Wansheng, Huang, Xiao Ru, Kim-Mitsuyama, Shokei, Truong, Luan D., Lan, Hui Y
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1401500/
https://ncbi.nlm.nih.gov/pubmed/16520412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.105.575589
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