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Synthesis by High-Efficiency Liquid-Phase (HELP) Method of Oligonucleotides Conjugated with High-Molecular Weight Polyethylene Glycols (PEGs)

The chemical modification of synthetic oligonucleotides has recently been investigated to improve their pharmacological utilization. In addition to chemical alterations of the backbone and of the heterocyclic bases, their conjugation with amphiphylic moieties, such as the polyethylene glycol has bee...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Bonora, GM, Zaramella, S, Veronese, FM
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Biological Procedures Online 1998
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC140118/
https://ncbi.nlm.nih.gov/pubmed/12734594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1251/bpo2
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