Comparative pharmacokinetics of caffeine and its primary demethylated metabolites paraxanthine, theobromine and theophylline in man.

The pharmacokinetics of caffeine (CA), paraxanthine (PX), theobromine (TB) and theophylline (TP) were studied in six healthy male volunteers after oral administration of each compound on separate occasions. The total plasma clearances of CA and PX were similar in value (2.07 and 2.20 ml min-1 kg-1,...

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Библиографические подробности
Главные авторы: Lelo, A, Birkett, D J, Robson, R A, Miners, J O
Формат: Artigo
Язык:Inglês
Опубликовано: 1986
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1401099/
https://ncbi.nlm.nih.gov/pubmed/3756065
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