Metoprolol metabolism and debrisoquine oxidation polymorphism--population and family studies.

The metabolism of metoprolol was studied in 143 unselected hypertensive patients and in 10 families. The log10 metoprolol to alpha-hydroxymetoprolol urinary ratio was bimodally distributed and was correlated with the debrisoquine oxidation phenotype (rs = 0.81, P less than 0.001). The results of the...

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Detaylı Bibliyografya
Asıl Yazarlar: McGourty, J C, Silas, J H, Lennard, M S, Tucker, G T, Woods, H F
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1985
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1400824/
https://ncbi.nlm.nih.gov/pubmed/2868742
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