Timolol metabolism and debrisoquine oxidation polymorphism: a population study.

1. The metabolism of orally administered timolol (T) to its ring cleavage ethanolamine (TE) and glycine (TG) products was studied in 108 unrelated hypertensive patients. 2. Statistically significant correlations between the 0-8 h urinary debrisoquine/4-hydroxy-debrisoquine ratio and the T/TE (rs = 0...

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Main Authors: Lennard, M S, Lewis, R V, Brawn, L A, Tucker, G T, Ramsay, L E, Jackson, P R, Woods, H F
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1379721/
https://ncbi.nlm.nih.gov/pubmed/2719899
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