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L-643.441: an H2-receptor antagonist with potent and long-lasting effects in man.

Submaximal dose pentagastrin tests conducted in normal male volunteers with L-643.441, a novel histamine H2-receptor antagonist, indicate that it is a potent and long-acting inhibitor of gastric acid secretion. The effect appears dose-dependent and single doses of 50 mg are sufficient to reduce secr...

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Detalhes bibliográficos
Main Authors: Henry, D A, Somerville, K W, Kitchingman, G K, Holmes, I B, Tobert, J A, Langman, M J
Formato: Artigo
Idioma:Inglês
Publicado em: 1985
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1400675/
https://ncbi.nlm.nih.gov/pubmed/2864050
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