Studies on the minimal lengths required for DNA primers to be extended by the Tetrahymena telomerase: implications for primer positioning by the enzyme

Telomerase is a specialized reverse transcriptase that contains an integral RNA subunit including a short template sequence. It extends telomeric 3′ overhangs and chromosome breakpoints by catalyzing reiterative copying of this internal template into single-stranded telomeric DNA repeats. Here we re...

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Main Authors: Baran, Nava, Haviv, Yonit, Paul, Beena, Manor, Haim
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2002
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC140050/
https://ncbi.nlm.nih.gov/pubmed/12490725
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