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A novel specificity for the primer-template pairing requirement in Tetrahymena telomerase.

Telomerase is a specialized reverse transcriptase with a built-in RNA template. Base pairing between the templating domain of telomerase RNA and a telomeric DNA primer is normally a characteristic of elongation of telomeric DNA. Here we demonstrate the mechanism by which Tetrahymena telomerase bypas...

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Autores principales: Wang, H, Gilley, D, Blackburn, E H
Formato: Artigo
Lenguaje:Inglês
Publicado: 1998
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170463/
https://ncbi.nlm.nih.gov/pubmed/9463392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.4.1152
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